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RESEARCH

Sigmabio is dedicated to continuing and advancing research in the field of tissue banking and documenting clinical evidence of human cellular and tissue-based products. At Sigmabio, we believe that every contribution, big or small, can make a difference in the journey towards a healthier future for all.

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Image by Joyce Hankins
Dentist holding X-ray
Dental X-ray Film

Allograft Processing & Sterilization

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As a result of allograft processing and sterilization, there is an exponential reduction in the potential for graft contamination, disease transfer, or both. With proper processing, allografts routine achieve the necessary sterility assurance level. 

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Our research involves studying different methods of processing and sterilization and their impact on the safety and quality of tissues. 

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Tissue Engineering

Sigmabio is dedicated to advancing research in the field of disease prevention and treatment. With a team of passionate scientists and researchers, we strive to make breakthrough discoveries that will improve the lives of individuals affected by various illnesses. Our commitment to innovation and collaboration drives us to explore new avenues in the fight against diseases. At Sigmabio, we believe that every contribution, big or small, can make a difference in the journey towards a healthier future for all.

Clinical Evidence

Bone grafts are often necessary to provide support, fill voids, and enhance biologic repair of skeletal defects. Autogenous bone recovered from the patient's own iliac crest is generally considered the gold standard of bone grafts. There is a need for alternatives, however, because of limited autograft quantities, donor site morbidity, and other problems including limited biologic performance.

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Allografts provide the alternative option, and they are bone grafts taken from one individual for transplantation to another. Bone allografts are being widely used in the field of dentistry, orthopedic, and craniofacial surgery. They are generally used in two forms: freeze dried bone allograft and demineralized freeze dried bone allograft.  

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It is important to document clinical evidence of this option and compare to other choices of bone grafts available to make informed decisions for patient's best outcome. 

Spinal X-ray Scan
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